What Is CBG?

Cannabigerol cannabinoid compounds in the female cannabis plant. CBG element in medical marijuana studies

What Is CBG?

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Cannabis plants contain over a hundred different types of substances (cannabinoids), from familiar THC (tetrahydrocannabinol) and CBD (cannabidiol) to less well-known CBG (cannabigerol). These cannabinoids react with bodies and brains, resulting in the myriad effects that cannabis products can have. Recent decades have brought expanded exploration into the health and wellness effects of many cannabinoids, and the outlook for many, including CBG, is promising.

How Is CBG Made?

In the cannabis plant, an enzyme triggers compounds found in the plants to form cannabigerolic acid (CBGA). CBGA is broken down into a number of sub-compounds, including three primary acids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).

When these acids are exposed to ultraviolet light or heat, they break down into cannabinoids, so that THCA becomes THC, CBDA becomes CBD and CBCA becomes CBC. Cannabigerol (CBG) is also formed in this process. In most strains of cannabis, CBG is only found at low concentrations (less than 1%) because most of the CBGA is converted into THCA and CBDA instead.

CBG’s promising future has prompted efforts to increase the volume of CBG production through genetic manipulation and by interbreeding different strains of cannabis plants. Scientific research into the cannabinoid generation process in plants has allowed scientists to precisely identify the peak stage of the cannabis flowering cycle, about ¾ through, for extracting the highest concentration of CBG from buds.Cannabis essential oil in the vial with a green leaf on a wooden table background with a copy space. Herbal medicine concept.

Benefits of CBG

Since ancient times, cannabis and its derivatives have been recognized and used for their health and wellness benefits, many of which are being further explored and rediscovered in laboratories around the world. Scientists now know that cannabinoids interact with the body’s endocannabinoid system (ECS) through their relationships with neurotransmitters in the brain and throughout the nervous system.

The ECS helps to regulate numerous basic functions and reactions including sleep, appetite, mood, immunity, stress, memory, and fertility. Natural cannabinoids are produced on demand whenever the ECS detects a need such as inflammation or hunger. Cannabis-based cannabinoids have been shown to enhance many of the functions that natural cannabinoids perform. Exploration into the positive effects of CBG is encouraging, with studies indicating benefits for:

  • Glaucoma: A recent study investigated the addition of CBG compounds to enhance the effectiveness of existing treatments for glaucoma.
  • Inflammatory Bowel Disease & Colitis: Several studies have indicated CBG as a likely aid to reducing the inflammation associated with IBD and colitis.
  • Colorectal Cancer: Cannabinoids, including CBG, appear in experiments to reduce tumor size and slow cancer growth.
  • Nausea: Long recognized for reducing nausea, CBG and other cannabinoids have been shown in multiple studies to ease this side effect of chemotherapy and other treatments and conditions.
  • MRSA Infections: CBG and other cannabinoids have antibacterial properties and have been utilized in topical treatments for decades. A recent European study found evidence that CBG can even be effective against methicillin-resistant Staphylococcus aureus(MRSA) infections, too.
  • Muscle Wasting & Severe Weight Loss (cachexia): Cannabis and increased appetite have a long history together, and CBG appears to show the benefits of appetite improvement without the psychotropic side effects of THC, particularly for patients undergoing chemotherapy.
  • Eating Disorders: This appetite stimulating effect of CBG may also have implications for treating eating disorders more effectively.
  • Inflammation: Studies with CBG and other cannabinoids have indicated these substances have neuroprotective qualities, meaning they may ease symptoms or slow the progression of neuroinflammatory conditions such as multiple sclerosis.
  • Bladder Conditions: CBG has been shown to ease overactive bladder conditions by blocking acetylcholine, the chemical messenger that tells the brain to launch bladder contractions.
  • Neurodegenerative Diseases: Recent investigations have shown promise using CBG to treat mice affected with Huntington’s disease and may be effective with related neurodegenerative conditions such as Parkinson’s and Alzheimer’s.

An infographic depicting the benefits of CBG.

At Loud Associates, we are committed to working with USDA-certified hemp growers to provide agricultural distribution of hemp products, and to create and offer the highest-quality CBD isolates and distillates, naturally derived from legal hemp varieties, for extractors, manufacturers, and wholesalers. Our superior CBD products are used in our own private label Prana hemp oil, extract, and balm, and our Pure HempSmokes. Please contact us to learn more about CBG and our other phytocannabinoid products.


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